EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

A THEMATIC REVIEW ON POTENTIAL ANTIMICROBIAL POTENTIAL APPLICATIONS OF BACTERIOCINS FROM LACTIC ACID BACTERIA

Nimra Riaz, Saleha Mahnoor Faheem and Muhammad Usman Ahmad*

ABSTRACT

The world-wide emergence of resistant pathogenic strains against the currently available antibiotics and the toxicity associated with them has compelled scientific community to increase their quests in finding other natural antimicrobial alternatives. In this regard recent discoveries on antimicrobial arsenals secreted by bacterial species against competing strains are gaining utmost importance not only because of their antimicrobial but also due to their anti-cancer potential. These natural bacterial arsenals are ribosomally synthesized low-molecular weight, heat stable, membrane active, proteolytically degradable and pore-forming, cationic peptides known as “Bacteriocins”. Owing to their anti-bacterial, anti-viral, anti-fungal, and anti-biofilm potential, bacteriocins seem to be the immediately available promising option for mitigation of AMR (antimicrobial Resistance) crisis and minimization of toxic effects of antibiotics on Host’s microbiome. The non-toxic and Generally Regarded as Safe (GRAS) status of Lactic acid bacteria (LAB) bacteriocins signifies their huge commercialization potential, and research on their biology is currently the most extensively studied subject of biotechnology. Their intrinsic food preservative and therapeutic potential can be enhanced by combinatorial approaches with other antimicrobial substances. However, their potential to be used as AGP (antimicrobial Growth Promoter) in animal production must also be evaluated. The initial half of this review focuses on the significance and biological aspects of LAB bacteriocins, while the latter half addresses the potential antimicrobial aspects of bacteriocins in various sectors.

Keywords: Bacteriocins, Antimicrobial Resistance, Biopreservation.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing