EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

WHAT IS THE PROFILE OF PATIENTS WITH TYPE 2 DIABETES AND NON-ALCOHOLIC FATTY LIVER DISEASE?

Sadikova Dildora Shukhratillaevna* and Khaydarova Feruza Alimovna

ABSTRACT

Prevalence of non-alcoholic fatty liver disease (NAFLD) increases dramatically. Type 2 diabetes (DM2) increases the risk of developing NAFLD, and the presence of NAFLD increases the risk of developing type 2 diabetes. The aim of our work was to study the profile of patients with NAFLD and DM2. We analyzed the profile of 582 patients treated at the Department of Diabetology of the RSSPMCE in 2019. 27% patients had non-alcoholic steatosis (NAS), 8% non-alcoholic steatohepatitis (NASH) based on fibroscanning after detection of steatohepatosis on liver ultrasound. Patients with NAS and NASH did not differ in gender, age, and glycemic control, from patients without NAFLD. 40% patients without NAFLD, 40% with NAS and 54% of patients with NASH had arterial hypertension, isolated diastolic hypertension (IDAH) occurred in 10.4% of patients with NASH, in 7% of patients with NAS, and in 5% of patients without NAFLD. Among patients without steatohepatosis diagnosed by ultrasound of the liver, there was a high proportion of people with an estimated NAFLD fibrosis score corresponding to stages 3-4 of fibrosis, which indicates the need for an active search for NAFLD in people with type 2 diabetes before the appearance of ultrasound signs of steatohepatosis in order to timely initiation of adequate treatment. We are continuing research to determine the optimal algorithm for the active search for NAFLD in people with type 2 diabetes.

Keywords: non-alcoholic fatty liver disease, type 2 diabetes, steatohepatosis, steatohepatitis.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing