EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

HYDROCORTISONE THERAPY FOR RELIEVING OF POST- TONSILLECTOMY PAIN: A RANDOMIZED, PLACEBO-CONTROLLED STUDY

Md. Hasanul Haque*, Md. Jaber-Al-Sayied1, Sonia Jahan Bithi, Habibur Rahman Palash, Nigar Sultana, H.M. Mustafizur Rahman , Md. Abdur Razzak and Md. Wahiduzzaman

ABSTRACT

Background: Post-operative pain following tonsillectomy is a common clinical problem faced by ENT surgeons. We investigated effect of two dose course of intravenous hydrocortisone in relieving pain following tonsillectomy. Materials & Methods: In this randomized, placebo-controlled trial, 40 consecutive patients between 20 and 40 years of age, who had no previous or known contraindications to steroid therapy, were randomly assigned at the time of surgery to either a two dose course of hydrocortisone (100 mg IV) or placebo; with the first dose administered during surgery and subsequent dose was given 12 hours following tonsillectomy. All of the patients were operated and treated by two same ranked surgeons. Postoperative pain was evaluated using visual analog scale. Results: In hydrocortisone group pain score was 6.55±0.76 & 2.65±0.87 at 1st & 7th POD respectively where as in placebo group pain score was 8.2±0.89 & 4.00± 0.92 respectively in 1st and 7th POD. There was significant pain reduction in IV hydrocortisone group. (P value 0.001) Conclusion: Application of 2 doses of hydrocortisone within 12 hours during and after tonsillectomy is advisable because of the reduction of postoperative pain.

Keywords: Tonsillectomy, hydrocortisone.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing