UTILIZATION OF NANOPARTICLES IN CNS DISORDERS, CURRENT AND FUTURE PERSPECTIVE: A MINI REVIEW

Vishal Kumar*

ABSTRACT

The field of nanomedicine is growing very fast with the development of different- different nanotechnologies day by day. NPs are able to provide potential benefit in the prevention and diagnosis of various CNS diseases, there is more possibility to develop new therapeutic strategies for completely eradicate the CNS diseases (AD, PD %& ALS) and also for the better diagnosis of CNS disease at earlier stage. Alzheimer’s and Parkinson’ diseases are considered more neurodegenerative diseases worldwide. There is complete understanding of pathology of these disease are unknown, the current therapy is available only for the neuroprotection and symptom management. Understanding of BBB pathophysiology will provide more specific therapy for the management of CNS diseases. Blood brain barrier (BBB) provides protection of brain, Researchers focuses to develop a novel NPs, carry the drug across the BBB and provide good bioavailability in the brain. Here I review the various neurological disorders and different NPs particularly the applications of NPs in diagnosis and treatment of CNS diseases. Collaboration between researchers, and material scientists is possible to develop a novel therapeutic strategy for the diagnosis sand management of CNS diseases.

Keywords: Nanoparticles, liposomes, nanoshells, utilization of nanoparticles/nanomaterials in Alzheimer’s, Parkinson’s & multiple sclerosis.