EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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 ICV - 79.57

Abstract

CHEMICAL CONSTITUENTS FROM THE AERIAL PARTS OF BARLERIA PRIONITIS L.

Imran Khan, Hinna Hamid, Mohammed Ali*, Mohammad Sarwar Alam, and Showkat Rassol Mir

ABSTRACT

Barleria prionitis L. (family Acanthaceae) is an erect, perennial, prickly, much branched shrub, used to treat catarrh, dropsy, dysuria, gastrointestinal disorders, jaundice, hepatic, nervine, paralytic and urinary disorders, rheumatism and sinusitis. This research work was proposed to isolate chemical constituents from the plant aerial parts and to characterize their structures. An ethanol extract of the aerial parts was adsorbed with silica gel for column, dried and chromatographed over a silica gel column packed in n-hexane. Various solvent mixtures of increasing polarity, viz., n-hexane, ethyl acetate and methanol were used to elute the column. The isolated chemical constituents were characterized as oleic acid (1), herniarin (7-methoxycoumarin, 2), 1-hydroxyanthraquinonyl (3→7′)-coumarin (3), 8-dehydroxyemodin-(5→5′)- 8′-dehydroxyemodin (4), n-tetracosane (5), (Z)-n-heptatriacont-8-ene (6), β- sitosterol n-octadec-9ʹ-enoate (β- sitosterol oleate, 7), stigmast-5,22–dien-3β –ol 3-O-α-D-glucopyranoside (8) and [1,1'-biphenyl]- 2,3,4,5,6, 2', 3', 4', 5',6'-decaol (9). Their structures were established on the basis of spectral data analysis and chemical reactions.

Keywords: Barleria prionitis L., aerial parts, extraction, phytoconstituents, isolation, spectral data, characterization.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia