AN OPEN LABEL CLINICAL STUDY EVALUATING THE EFFECT OF SHAMANA SNEHANA WITH SHATAPAKI KSHEERABALA TAILA IN MARGAVARANAJA PAKSHAGHATA/ISCHEMIC STROKE

Saritha A. K.*, G. Shrinivasa Acharya and Shailesh Y.

ABSTRACT

Background: Shamana snehana form the sheet anchor of treating chronic debilitating disorder like Pakshaghata. Ksheerabala bala taila is the ideal prescription in this regard and the fortification of the same as Shatapaki Ksheerabala taila is used, thereby enhancing the therapeutic efficacy. This study is planned to evaluate the effect of Shatapaki Ksheerabala taila in the patients suffering from Pakshaghata. Objectives: To evaluate the therapeutic effect of Shatapaki Ksheerabala taila in reducing the symptoms of Margavaranaja Pakshaghata/Hemiplegia due to ischemic stroke and to measure the improvement in the health related quality of life attained following the medication. Study design: Study Type: Interventional; Allocation: Non randomized; End point classification: Efficacy study; Intervention Model: Single group assignment; Masking: Open label; Primary purpose: Treatment. Setting: 30 patients selected from OPD & IPD of Sri Dharmasthala Manjunatheshwara College of Ayurveda & Hospital, Udupi. Intervention: Oral administration of Shatapaki Ksheerabala taila in a dose of 24 ml in the morning in empty stomach about half an hour before breakfast along with 150 ml of warm water. Outcome measures: The efficacy of the treatment was assessed based on the primary and secondary outcome measures which are Muscle power of upper and lower limb, Muscle Spasticity of upper and lower limb, Pain, Berg balance scale and Stroke specific quality of life scale at a time frame of Day 0 and Day 28. Wilcoxon Signed Rank test was used to assess the statistical analysis of the data. Results: Shatapaki Ksheerabala taila is found to be effective in the remission of the symptoms of Margavaranaja Pakshaghata as evidenced by statistically significant reduction in the symptom score of primary and secondary outcome measures. Conclusion: Shatapaki Ksheerabala taila is proved to be efficacious in reducing the symptoms of Margavaranaja Pakshaghata and hence improving the Quality of Life.

Keywords: Margavaranaja Pakshaghata; Ischemic stroke; Shatapaki Ksheerabala taila.