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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57



Irshad Ahmad Lone, Mohammad Ali*, M. Sarwar Alam, Showkat Rasool Mir and Shahnaz Sultana


Didymocarpus pedicellatus R.Br. (family Gesneriaceae) is a small stemless herb used to treat chest pain, cough, cuts, diabetes, diarrhoea, epilepsy, heart and renal diseases, bladder and kidney stones, splenitis, stomach ache, syphilis, ulcers and wound. The present study was designed to isolate and characterize chemical constituents of the aerial parts of D. pedicellata. Phytochemical investigations of a chloroform fraction of the alcoholic extract of aerial parts resulted in the isolation of 4-(hept-7-enyl) – phenol (p-heptenyl phenol, 1) and four aliphatic acids identified (all Z)- n-hexacosa-9, 19, 21-trienoic acid (2), n-hexacosa-8 (Z)- en-l-oic acid (3), n-hexacosa-10 (Z)-enl-oic acid (4) and (all Z)- n-octacosa-5, 15,19, 22-tetraen-l-oic acid (5). GC-MS analysis of a petroleum ether fraction of the alcoholic extract of the aerial parts showed high amounts of aliphatic alcohols (49.3 %) and aliphatic esters. The predominant components were n-heneicosan-1,6-diol (44.5 %), glyceryl oleate (22.7 %) and glyceryl linoleate (6.8%). The other aliphatic alcohols detected in small amounts included n-tetradec-5,7,9-trien-1-ol, n-nonadec-9,11,13-trien-1-ol, n-nonadec-6,10,13-trien-9-ol and 1-phenyl-n-docos-11-en-2,3,6-triol.

Keywords: Didymocarpus pedicellatus, aerial parts, ethanolic extract, phytoconstituents, isolation, characterization.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia