FORMULATION AND EVALUATION OF HERBAL GEL FOR TREATMENT OF RECURRENT APHTHOUS STOMATITIS (RAS)

Bariki Rajasekhar*, B. Srivani eeswari, C. Lakshmanna, G. Ishwarya Deepika, M.G. Kaveri, K. Rajeswari Raziya, P. Praveen Kumar

ABSTRACT

Herbal formulation have growing demand in the world market. Herbal medicines are the oldest form of health care known to mankind. The objectives of present investigation were to formulate and evaluate herbal gel for treatment of Recurrent aphthous stomatitis(RAS). Herbal gel was prepared by using aqueous extracts of guava, neem, tulasi and different concentration of Carbopol 940, Guargum as a gel base. Formulations were evaluated for various parameters like physical appearance, pH, homogeneity, spreadability, viscosity, extrudability. However, the Carbopol 940 based F3 Herbal gel proved to the formula of choice, since it showed the highest percentage of good spreadability, extrudability, and rheological properties. Formulation F3 with 1 % leaves extract herbal gel showed best results because all the parameter showed satisfactory results.

Keywords: Guava, Neem, Tulasi, herbal formulation, herbal gel, ulcer treatment.