A CLINICAL STUDY TO EVALUATE THE EFFECT OF GUDUCHI GHANAVATI IN SMRUTHI BHRAMSHA/ ALZHEIMER’S DISEASE
Sahana M. N.*, Shrilatha Kamath T. and Dhaneshwari H. A.
Objectives: Objective for the study includes answer to the research questions or the hypothesis that is set. Present study was conducted to evaluate the therapeutic effect of Guduchi ghanavati in Smruthi bhramsha/ Alzheimer‟s disease. Method: Interventional non-randomized open labelled single group study with pre-test and post-test design. Twenty patients diagnosed with Smruthibhramsha/Alzheimer‟s disease satisfying inclusion and exclusion criteria were selected from OPD/IPD of SDM Ayurveda Hospital, Udupi. The selected patients were administered with three capsules of 500 mg of Guduchi Ghana in early morning on empty stomach with lukewarm water. Statistical analysis was done using students paired „t‟ test and Wilcoxon signed rank test. Result: Percentage of relief is seen in QOL-informant and patient version is 9.04% and 14.712% respectively. In clinical dementia rating score, dementia severity rating scale and Global deterioration Scale is 19.28% and 7.282%, 9.091% betterment is seen respectively. In parameters like grahana 32.727%, dharana 33.33%, smarana 20.75% improvement is noticed. Conclusion: Three capsules of Guduchi ghanavati have shown significant improvement in Smruthibhramsha/Alzheimer‟s disease. The efficacy of the medication has been proved with the statistical analysis of the parameters.
Keywords: Smruthi bhramsha, Alzheimer’s disease, Guduchi.
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