ANTIHISTAMINIC DRUGS UTILIZATION AMONG PAEDIATRIC POPULATION OF A SECONDARY CARE HOSPITAL IN ERNAKULAM DISTRICT OF KERALA, INDIA

Jeena Jacob, Amratha K. Thomas, Jesteena J. and Shaji George*

ABSTRACT

Background and Objectives: In paediatrics, first generation antihistaminic drug prescribing is a common practice for treating allergic conditions for many years. The aim of the study is to comprises the indications for use as well as safety and efficacy of newer antihistamines used in paediatric population. Patients and Methods: The study conducted was a prospective observational study on antihistamine utilization and carried out for a period of 6months in the department of paediatrics in a private hospital. The study involved, 100 paediatric patients with inclusion criteria of patients admitted in the department of pediatrics (under 12 years). Results: From the total sample of 100, about 60% receiving at least one antihistamine, out of which 81.6 % received first generation antihistamines and 38.3 % received multiple antihistamines. The total 6.6% showcased adverse drug reaction indicating need for pharmacist intervention. Conclusion: The study concluded by stating that the first-generation antihistamines were most commonly prescribed for paediatric population and the reason was its safe utilization for decades as well as their sedating property in patients with allergic rhinitis and urticaria.

Keywords: Antihistamines, Paediatrics, Drug Utilization, Interventions, Indications, ADR.