GREEN NANOTECHNOLOGY A BOON IN SILVER NANOPARTICLE (AgNPs) SYNTHESIS- CERTAIN ASPECTS OF AgNPs BIOMEDICAL APPLICATIONS AND AN OUTLINE OF ITS TOXICOLOGICAL IMPACTS - A MINIREVIEW
Shazia Khan, Dr. Ayesha S. Ali and Dr. Sharique A. Ali*
Silver nanoparticles due to its vast applications in medical and physiochemical field have received global attention. Earlier they were synthesized by chemical and physical methods which due to their shortcoming are replaced by green synthesis using microorganisms and plants. Green nanotechnology has made the synthesis of nanoparticles cost effective, hazard free, faster and eco-friendly. Silver is used as an antimicrobial agent since long back; with the advent of antibiotics there use was decreased. Due to the rise in drug resistance, the scientists are focusing on the use of silver due to its oligodynamic action with antibiotics/drugs to enhance their efficacy. Apart from this due to its antimicrobial activity it is used in stents, catheters, orthodontic and orthodontic implants, water purification systems, cosmetics, agriculture, paints etc. It is expected that the use of silver nanoparticles will escalate in future due to its various antimicrobial properties which indicate huge production and usage of silver nanoparticles. This large scale production and usage will lead to toxicological impacts on the humans, animals and environment; the area that still needs exhaustive research. In this review paper we are exploring the potential of different biological sources for green synthesis of silver nanoparticle, their applications and outline the toxicological effects of excessive use of silver nanoparticles in future.
Keywords: nanotechnology, nanoparticles, silver, microorganisms, green synthesis, toxicity.
[Full Text Article]