ANALYTICAL TECH NIQUES FOR ELEMENTAL ANALYSIS: A REVIEW

*Dutta Ankita, Jindal Diksha, Patil R. K. and Patil H. C.

ABSTRACT

Analytical chemistry is the study of analytical techniques and their instrumentation which play a very essential role in determination and evaluation of the quality of pharmaceutical preparation and various elements present in samples.[12] The pharmaceuticals development shows their efficacy if the presence of impurities is not detected in the sample.[5] Therefore, several analytical methods are developed time to time in order to estimate the pharmaceutical matter. For determination of inorganic elements several techniques used is atomic absorption spectrophotometer and inductively coupled plasma atomic emission spectrometry. For the trace element analysis inductively coupled plasma atomic emission spectrometry (ICP-AES) is used and atomic absorption spectrometry is used for the determination of environmental samples as well as industrial toxicology. X-ray fluorescence spectroscopy (XRFS) is a type of analysis technique for qualitative and quantitative determination used mainly for determination of heavy metals. The relevant use of analytical methods of which is remarked to employ more efficient and fast techniques which is certified by pharmaceutical quality control. Further, Graphite furnace atomic absorption spectroscopy, Cold vapour atomic absorption spectrometer (CVAAS), Atomic emission and fluorescence spectroscopy (AES and AFS), Inductively Coupled Plasma Mass spectrometry (ICP-MS) are also the various analytical techniques.[1,2]

Keywords: Analytical techniques, atomic absorption spectrophotometer, X-ray fluorescence spectroscopy, inductively coupled plasma atomic emission spectrometry, pharmaceutical quality control.