CASE SERIES ON AUTOIMMUNE-BULLOUS DISEASE
Dr. Remya Radhakrishnan*, Dr. Jibin Jacob Chacko, Dr. Chinnu Jacob, Dr. Priscilla Mary J., Dr. S. Haja Sherief and Dr. T. Sivakumar
The autoimmune bullous disease is a rare disorder affecting skin and mucosa. In an autoimmune disease, the body’s immune system which normally protects the body against foreign invaders mistakenly attacks the skin cells resulting in the formation of blisters. A blister is an accumulation of fluid between cells of the epidermis and upper epidermis. The cause of the blister could be either genetic or immunological. Based on its location of intraepidermal and subepidermal, pemphigus Vulgaris constitute intraepidermal immunobullous disease whereas bullous pemphigoid is a subepidermal immunobullous disease. Bullous pemphigoid is a chronic autoimmune skin disorder resulting in generalized, pruritic, bullous lesions, and Pemphigus Vulgaris is an uncommon, potentially fatal, autoimmune disorder characterized by intraepidermal blisters and extensive erosions on apparently healthy skin and mucous membrane. Treatment strategies for both bullous pemphigoid and pemphigus Vulgaris include Topical and systemic corticosteroid initially and long term maintenance therapy with immunosuppressants. To observe the treatment pattern, a case series with three cases on pemphigus Vulgaris and one case on bullous Phemphigoid is highlighted and analyzed below.
Keywords: Autoimmune, Bullous Pemphigoid, Pemphigus, Corticosteroid, Case Report.
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