EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

PHYTOCHEMICAL AND IN-VITRO PHARMACOLOGICAL EVALUATION OF IPOMOEA SEPIARIA AGAINST SELECTED PATHOGENIC MICROORGANISMS.

B. Prasanna Kumar*, K. Sravanthi, Pavan Kumar Chadalawada, B. Pooja, K. Vadivel

ABSTRACT

Background: Convolvulaceae - The Morning Glory Family, the genus Ipomoea since time immemorial have been in continuous use for different purposes, such as nutritional and somany importand medicinal values. There is no much more work was carried out on this species. Objective: To Study the preliminary phyto chemical parameters and in-vitro antimicrobial and anthelmintic acitvity on selected medicinal plant crude extract. Materials and Methods: In the present study antimicrobial activity of petroleum ether and ethyl acetate extracts from the leaves of Ipomoea sepiaria and phytochemicals was evaluated with Gram-positive and Gram-negative bacteria. The fungi employed for screening were Aspergillus niger and Candida albicans. Leaves were dried, powdered and extracted with soxhlet apparatus. In-vitro antibacterial and antifungal activity was performed by the agar diffusion method at concentrations of 50mg/mL to 150mg/mL. Ciprofloxacin (10 μg/mL) and Fluconazole (10μg/mL) was employed as antibacterial and antifungal reference standard to compare the results. Anti-helminthic activity also performed by using Pheretima posthuma. paralysis and death time was monitored. Albendazole was used as standard. Results: It has been observed that all the tested extracts showed mild to moderate activity against the bacteria and fungi whereas higher concentration of petroleum ether extract and ethyl acetate extract 150mg/mL were found to be most promising antibacterial activity and shows highest activity towards gram positive organisms. Plant extract shown comparable anthelmintic activity to that of albendazole as standard. Conclusion: We concluded that the petroleum ether and ethyl acetate extracts of Ipomoea sepiaria leafhave mild activity against bacteria and fungus but it revealed significant anthelmintic activity.

Keywords: Albendazole, Ciprofloxacin, Fluconazole, Ipomoea sepiaria, Pheretima posthuma.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 November 2021 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR: NOVEMBER ISSUE PUBLISHED

    NOVEMBER Issue has been successfully launched on 1 November 2021.

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )