EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EVALUATION OF ANTIMICROBIAL ACTIVITY OF LEAF EXTRACT OF TINOSPORA CORDIFOLIA ON URINARY TRACT INFECTION (UTI) CAUSING PATHOGENIC BACTERIA

Madan Mohan Gunda* and Rani Kommidi

ABSTRACT

Urinary tract infection (UTI) has become a more grievous problem today, due to multidrug resistance of infecting Gram-positive (GP) and Gram-negative (GN) bacteria, sometimes even with multiple infections. This study examines effectivity of Tinospora cordifolia Tropical flowering plant. T. cordifolia or “Guduchi” is a well-known medicinal plant studied extensively since ancient times. This article specifically describes the role of T. cordifolia as an antimicrobial agent and as an immunity enhancer plant. Pathogenic bacteria were isolated from urine samples of 70 school going children and were sent to AMPATH for Urine culture Antibiograms of 4 isolated bacteria (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia and Enterococcus faecalis ).were isolated from urine samples were ascertained by the disc-diffusion method, and antibacterial effectivity of plant extracts was monitored by the agar-well diffusion method. Isolated bacteria were floridly MDR (Multi Drug Resistant Bacteria) to most antibiotics of the day. Methanol extracts of T. cordifolia plant were used, and extracts at least caused 25–29 mm as the maximum size of zone of inhibition on bacterial lawns. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of methanol extracts of T. cordifolia plant were recorded. The Ethanol extract of P. aeruginosa, had 4.08 mg/ml as the lowest MIC value and 8.37 mg/ml as the lowest MBC value, against signifying effectivity; but it had the highest MIC value of 9.68 mg/ml. and the highest MBC value of 24.07 mg/ml for most other MDR bacteria including Escherichia coli. Qualitative phytochemical analysis was done for these T. cordifolia plant, which can be promoted as complementary medicine. In the present study, we examined the anti-microbial effects of dried and powered leaves of T. cordifolia. were extracted with Ethanol, Ethyl acetate, and hexane Solvents were used, process followed by soxhelt extraction.

Keywords: Medicinal plant; Tinospora cordifolia; solvent extracts; anti-oxidant activity and, Ethanol extract.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 September 2020 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR SEPTEMBER ISSUE PUBLISHED

    SEPTEMBER 2020 Issue has been successfully launched on 1 September 2020.

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing