EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

FORMULATION AND EVALUATION OF TOOTHPASTE WITH BROMELAIN AND TULSI EXTRACT FOR DENTAL CARIES

R. Gowri*, S. Dhanalakshmi, P. Nandhini, S. Maheswari, S. Pooja, P. Kavitharaninachiya and K. Surya

ABSTRACT

In India, remarkable dental problems are due to microbial infections. Dental problems are classified in to three types, formation of dental plaques, dental caries and periodontal diseases. When plaque accumulates on tooth surface due to biochemical reactivity of complex micro-organisms leads to dental caries.The perpetual and most common disease today is Dental caries also known as tooth decay. The prime application of toothpaste is elimination of bacteria in mouth and to promote oral cleanliness. The essential criteria being the toothpaste should impart abrasive action and good breath. Herbal toothpaste must ascertain oral hygiene at reliable low cost and it freshen our breath by preventing various gum diseases. Herbal toothpaste is entirely destitute of harmful chemical substances liable for tooth staining and altered taste. Plaque formation begins with the formation of a glycoproteinaceous pellicle layer, constituted from components of saliva, crevicular fluid, host and bacterial cells. Though the pellicle layer primarily serves as a protective barrier, it also acts as a substrate for bacterial accumulation which invariably forms dental plaque. Hence considerable attention turned on natural ingredients used for the treatment of dental plaque. Pineapple is the common name of Ananascomosus (syns. A. sativus, Ananassa sativa, Bromeliaananas, B. comosa). Pineapple is the leading edible member of the family Bromeliaceae, Bromelain is a chief protease enzymes found in pineapple plant (Ananascomosus). Hence the main aim is to formulate and evaluate herbal toothpaste containing Bromelain and Tulsiextract that removes plaque and promotes the oral hygiene.

Keywords: Dental carries, Tooth Paste, Bromelain, Tulsi.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia