FORMULATION AND EVALUATION OF TOOTHPASTE WITH BROMELAIN AND TULSI EXTRACT FOR DENTAL CARIES
R. Gowri*, S. Dhanalakshmi, P. Nandhini, S. Maheswari, S. Pooja, P. Kavitharaninachiya and K. Surya
In India, remarkable dental problems are due to microbial infections. Dental problems are classified in to three types, formation of dental plaques, dental caries and periodontal diseases. When plaque accumulates on tooth surface due to biochemical reactivity of complex micro-organisms leads to dental caries.The perpetual and most common disease today is Dental caries also known as tooth decay. The prime application of toothpaste is elimination of bacteria in mouth and to promote oral cleanliness. The essential criteria being the toothpaste should impart abrasive action and good breath. Herbal toothpaste must ascertain oral hygiene at reliable low cost and it freshen our breath by preventing various gum diseases. Herbal toothpaste is entirely destitute of harmful chemical substances liable for tooth staining and altered taste. Plaque formation begins with the formation of a glycoproteinaceous pellicle layer, constituted from components of saliva, crevicular fluid, host and bacterial cells. Though the pellicle layer primarily serves as a protective barrier, it also acts as a substrate for bacterial accumulation which invariably forms dental plaque. Hence considerable attention turned on natural ingredients used for the treatment of dental plaque. Pineapple is the common name of Ananascomosus (syns. A. sativus, Ananassa sativa, Bromeliaananas, B. comosa). Pineapple is the leading edible member of the family Bromeliaceae, Bromelain is a chief protease enzymes found in pineapple plant (Ananascomosus). Hence the main aim is to formulate and evaluate herbal toothpaste containing Bromelain and Tulsiextract that removes plaque and promotes the oral hygiene.
Keywords: Dental carries, Tooth Paste, Bromelain, Tulsi.
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