FORMULATION AND EVALUATION OF PARACETAMOL TABLET TO ASSESS THE BINDING PROPERTY OF SWEET LEMON PEEL PECTIN
*Maheshwari M. Bhongade, Shubham B. Kale, Avinash O. Maske and Yogeshwary M. Bhongade
The aim of present work was to extract pectin from dried as well as wet sweet lemon fruit peels to assess its binding property in tablets using paracetamol as a model drug. Firstly sweet lemon peel or its powder was subjected to simple water heating extraction method and pectin was isolated using ethanol as precipitating agent. Then after four batches were formulated using pectin in different proportions. Precompression and post compression studies were perform for each formulation. The results obtained for all precompression and post compression parameter were found within acceptable range of pharmacopoeias. On the basis of peel pectin can act as a excellent binder in dosage forms. Since it is of natural origin and sweet lemon peel available at low cost it may prove to be better binder over commercially used synthetic binders.
Keywords: Binding property, Sweet lemon peel pectin, Simple hot water based extraction.
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