EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

INVESTIGATION OF THE PHOLCUS PHALANGIOIDES SPIDER WEB FOR ANTI BACTERIAL ACTIVITY

Vijimole P. J.*, Aswathy V. and Dr. Rosaline Mary

ABSTRACT

Spiders are one of the most successful predators, they are equipped with natures wondrous material known as spider silk. Spider silk extracts were prepared by using the solvent Dimethyl sulfoxide. The present study was based on the anti-bacterial properties of the Pholcus phalengioides commonly known as cellar spider web. For the assessment of its inhibitory activity four pathogenic bacterial strains Staphalococcus aureus, Bacillus subtilis, Pseudomonas aeuroginosa and Escherichia coli were used, where standard Gentamycin (80 mcg) was kept as positive control. Antibacterial activity was evaluated by Muller Hinton agar well diffusion method. Two different concentrations (400 mcg) and (800 mcg) of web extracts were used for the experiment. Spider web showed antibacterial activity against four bacterial strains. The spider silk induced the highest inhibition zone against Bacillus subtilis, followed by Staphylococcus aureus and Psuedomonas aeruginosa. The silk showed least effectiveness against Escherchia coli. Moreover, the inhibitory potential of silk varied with the concentrations of the silk solution. This study provides clues to the role of spider web extract in treating the pathogens effect of different microbes.

Keywords: Spider silk, Pholcus phalengioides, anti-bacterial properties, inhibition zone, bacteria - Staphalococcus aureus, Bacillus subtilis, Pseudomonas aeuroginosa and Escherichia coli,).


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )