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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

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European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Ezeudo Ewuziem Nwaozuzu* and Godwin Chukwu Ebi


Monodora myristica (fam. Annonaceae) is one of the antimalarial plants in Ibo-Nigeria folkloric medicine with claims of antimicrobial and antifungal properties which have been confirmed by the authors in preceding preliminary studies. The Monodora plant is an ornamental tree with a height of up to 30m high, dense foliage and spreading crown. It flowers from September to April at which time the new leaves appear. The fruits are produced between April and September. They are about 15cm in diameter, green, round, woody and are suspended in a long stalk. The pulp is white and contains numerous seeds of about 2.5cm long. Previous preliminary studies on the plant’s seed by the authors showed that the ethylacetate-soluble fraction of its methanolic extract possess significant and higher antimicrobial properties than the ethylacetate-insoluble fraction. The study was therefore designed to evaluate the antimicrobial properties and potential therapeutic applications of the the ethylacetate-soluble constituents of the plant’s seed. Monodora myristica seeds were sun-dried, milled and extracted by cold maceration with 95% methanol. This methanolic extract was further fractionated with ethylacetate to obtain an ethylacetate-soluble fraction and an ethylacetate-insoluble fraction. The constituents of the ethylacetate-soluble fraction were then isolated by PTLC using pre-coated alumina and silica gel GF254 plates.

Keywords: Monodora myristica, Phytochemistry, Ethylacetate fractions, Preparative thin layer chromatography, Ibo-Nigeria folkloric medicine.

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )