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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Saqlain Haider, Mohammad Sarwar Alam, Hinna Hamid, Mohammed Ali* and Showkat Rassol Mir


Adiantum capillus-veneris L. (family Pteridaceae) is an aromatic, non-flowering fern with a creeping rhizome. Its fronds are used to treat chest diseases, headaches, insanity, jaundice and menstrual complaints. This research work was proposed to isolate chemical constituents isolated from the plant fronds and to characterize their structures. An ethanol extract of the fronds was fractionated with petroleum ether, ethyl acetate and methanol. The ethyl acetate fraction was adsorbed with silica gel for column, dried and chromatographed over a silica gel column packed in n-hexane. Various solvent mixtures of increasing polarity, viz., n-hexane, ethyl acetate and methanol were used to elute the column. The isolated chemical constituents were characterized as pentacyclic triterpenes (fern-9(11)-ene, 1), 3-α-hydroxyfernane (farnan-3α-ol, 3), farnan-3β, 16β-diol (4) and betulinic acid (5), an aromatic ester identified as 16′-methyl n-heptadecanyl 3,4-dihydroxybenzoate (2) and a rare diglucoside α-Dglucopyranosyl-(6→1′)-O- α-D-glucopyranoside (6). Their structures were established on the basis of spectral data analysis and chemical reactions.

Keywords: Adiantum capillus-veneris, fronds, extraction, phytoconstituents, isolation, spectral data, characterization.

[Full Text Article]




    AUGUST Issue has been successfully launched on 1 August 2022.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database