EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

CLINICAL EVALUATION OF SAHACARADHI KASHAYA AND MAHARASNADHI KASHAYA ALONG WITH JATAMAYADHI UPANAHA SWEDA IN JANU SANDHIGATA VATA W.S.R TO OSTEOARTHRITIS

Shereen Sreenivas*, Muralidhara and Sindhura A. S.

ABSTRACT

Background: Janu Sandhigata Vata is a chronic, degenerative, inflammatory disease of the knee joint which has a great impact on the quality of the life of an individual. The clinical features of Sandhigata Vata resemble Osteoarthritis mentioned in contemporary science. In this clinical study, total 43 patients having the complaints of Janu Sandhigata Vata (Osteoarthritis) were randomly divided into 2 groups. In Group A, patients were treated with Sahacaradhi Kashaya and Jatamayadhi Upanaha Sweda. Group B were treated with Maharasnadhi Kashaya and Jatamayadhi Upanaha Sweda. These formulations were considered for the study due to its wide applicability and availability. Objective: To compare the efficacy of Sahacaradhi Kashaya and Jatamayadhi Upanaha Sweda to that of Maha Rasnadi Kashaya and Jatamayadhi Upanaha Sweda in the management of Janu Sandhigata Vata w.s.r to Osteoarthritis knee joint. Materials and Methods: In a total of 43 patients, 22 patients of Janu Sandhigata Vata were selected and administered with Sahacaradhi Kashaya (24 ml twice a day before food) and the other 21 patients were given Maharasnadhi Kashaya (24 ml twice a day before food) internally for 14 days with Jatamayadhi Upanaha Sweda (common for both the groups) externally for a span of 7 days. The patients were assessed through WOMAC index and Lakshanas of Janu Sandhigata Vata before, mid and after the treatment respectively. The results were analysed statistically using SPSS VER.20.Observation & Results: Clinical data was collected and analysed statistically using Wilcoxon Sign rank test to compare the Mean value within the groups and Mann Whitney ‘U’ test to compare the Mean difference values between the groups for the subjective parameters. 40 patients completed the study. Statistical significance was observed in the subjective parameters. Interpretation & Conclusion: It is concluded from the study that most of the symptoms subsided by seven days in both the groups. The data shows that the combined effect of Maharasnadhi Kashaya and Jatamayadhi Upanaha Sweda i.e. group B had an edge over Group A in the management of Janu Sandhigata Vata.

Keywords: Janu Sandhigata Vata, Sahacaradhi Kashaya, Maharasnadhi Kashaya, Jatamayadhi Upanaha Sweda.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing