EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

PREVALENCE OF THYROID DYSFUNCTION IN SCHIZOPHRENIA

Anjalika Goyal* and Piyush Verma

ABSTRACT

Schizophrenia is a complex and pathological brain developmental disorder with multiple neurotransmitters abnormalities. The most commonly affected neurotransmitters are dopamine, serotonin, glutamate, and GABA. Thyroid hormone plays important role in brain development and also modulates all these neurotransmitters. Association between mental state and thyroid function has been long recognized since the earliest description of myxedema and thyrotoxicosis. But its role in psychotic disorder is often ignored and rarely assessed. This study was planned to study prevalence and type of thyroid dysfunction in schizophrenia. A present study is conducted on 100 patients newly diagnosed with schizophrenia using ICD-10 criteria from department of psychiatry. Serum Thyroid stimulating hormone (TSH), T3 (triiodothyroxine) and T4 (L-thyroxine) levels were estimated by radioimmunoassay technique. The data were analyzed using Chi-square (χ2) test. Out of 100 patients 27 patients were found to have abnormal thyroid function test, from which 4 were hyperthyroidism and 23 were hypothyroidism. These finding suggests there is high prevalence of thyroid abnormality in patients suffering from schizophrenia. So patients with schizophrenia-spectrum disorders should be screened for abnormal thyroid hormonal status.

Keywords: Schizophrenia, Thyroid Dysfunction, Hypothyroidism, and Hyperthyroidism.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing