A SHORT REVIEW ON USES OF HARBAL DRUGS IN CARDIOVASCULAR DISEASES

Ab. Ahesan Ab. Faruk*, Mohd. Saad Mohd. Zafar Husain, Mohammed Zahid Mohammed Firoz, Syed Abdul Zahed Syed Abdul Wahed, Anis Shah Akram Shah, Mohammad Raza Khan Nasir Khan and Mohd. Rizwan Shaikh Ibraheem

ABSTRACT

Herbal medication are commonly used for clinical purposes including treatment of cardiovascular conditions full stop compared with conventional medication herbal medication to not require clinical studies for their marketing for formal approval from regulatory agencies and for this reason their efficacy and safety are rarely proven.In this review we summarise available evidence on herbal medication mostly in cardiovascular medicine. We show that the use of this medication for the treatment of cardiovascular disease is often not supported by scientific evidence. Despite most of these herbs showing effect on biological mechanism related to the cardiovascular system data on their clinical effects are leaking. Potential relevant side effects including increased risk of drug interactions are described and the possibility of contamination of substitution with other medication represents a concern should always assess the use of herbal medication with patients and discuss the possible benefits and side effects with them. Herbal matterials have been used as medical treatments since the starting of human civilization and some derivatives (Example as Aspirin, reserpine and digitalis) have become main stays of human pharmacotherapy. 4 cardiovascular diseases herbal treatment have been used in patients with congestive heart failure, satolic hypertension, angina pectoris, atherosclerosis, cerebral insufficiency, venous insufficiency and arrhythmia. How ever mini herbal remedies used today have not undergone careful scientific assessment and some have the potential to cause serious toxic effects and major drug to drug interactions.

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