REVIEW ON ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF WRIGHTIA TINCTORIA R. BR.

Dr. Amritha E.*, Sajeena CH, Dr. Shijikumar P. S., Dr. Sirajudheen M. K. and Sherin A.

ABSTRACT

Wrightia tinctoria is an ayurvedic remedy in various ailment including antioxidant and antimicrobial activity. Wrightia tinctoria is extensively used in Indian system of medicine is a small deciduous tree of the family apocynaceae. The plant is very useful as stomachic antidysentric and diuretic used in the treatment of abdominal pain, skin disease and bilious affection. The major phytoconstituents are beta-amyrin, cycloeucalenol, cholesterol, methylcholesterol. Antioxidant potential was determined by 2,2diphenyl-1-picryl hydrazyl (DPPH) radical scavenging activity and 2,2 azino -bis-3-ethyl benzothiazoline-6-sulphonic acid(ABTS)radical action decolourisation assay also antimicrobial activity of different extract of wrightia tinctoria has been studied against human pathogenic bacterial strains, E.coli, bacillus subtilis, streptococcus aureus and pseudomonal aerugenosa by disc diffusion method on agar. The finding showed potential antibacterial properties of extract against organisms. The result obtained appeared to conform the antimicrobial and antioxidant activity that support the ethanopharmacological uses of wrightia tinctoria.

Keywords: wrightia tinctoria, antimicrobial activity, antioxidant activity. Corresponding auther: Amritha E,Jamia salafiya pharmacy college, pulikkal.