REVIEW ON NEUROPROTECTIVE ACTIVITY OF HERBAL DRUGS

Aditi Mukherjee*, Madhulika Yadav, Adity Shaw, Afsar Alam, Susmita Basak, Supradip Mandal, Arpita Biswas, Dr. Dhrubo Jyoti Sen and Dr. Beduin Mahanti

ABSTRACT

Neuroprotection is the preservation of the structure and function of neurons from insults arising from cellular injuries induced by a variety of agents or neurodegenerative diseases (NDs). The various NDs including Alzheimer’s, Parkinson’s, and Huntington’s diseases as well as amyotropic lateral sclerosis affect millions of people around the world with the main risk factor being advancing age. Neurodegeneration refers to a condition of neuronal death occurring as a result of progressive disease of long-term and is becoming a major health problem in the 21st century. Natural products play a very essential role in preventing and providing therapeutic effect to various neurodegenerative diseases, and neuronal dysfunctions. Plant secondary metabolites include an array of bioactive constituents’ form both medicinal and food plants able to improve human health. In this review, we presented classical examples of plant-derived neuroprotective agents by highlighting their family, parts used, geographical location and their uses for the neuro protective activity.

Keywords: Neurodegenerative Disease, Nervous Disorder, Ataxia, Ischemic Stroke, Alzheimer’s disease, Dementia.