EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

REVIEW: TOXICITY OF THE MYCOTOXINS A POTENTIAL RISK FACTOR IN HEALTH

Krishnendhu*, Nasiya N., Jerrin Jose K., Dr. Shijikumar PS., Dr. Sirajudheen M. K. and Sherin A.

ABSTRACT

Mycotoxin are naturally occurring toxic metabolites of fungi, that may be present in food product. Mycotoxinss encompass a wide spectrum of different chemicals and they effect many target organ and system, notably the liver, kidney, nervous system, endocrine system and other immune system. They are frequently found in product such as nuts, corn, rice etc. Five most important naturally occurring mycotoxin in human food and animal feed are aflatoxin, ochratoxin, deoxyvalenol, zearalenone and fumonisin. Most countries have established maximum tolerated levels for total aflatoxins ranging from 4-20ng/g . conventional risk assessment has helped manage the risk form of mycotoxin in developed countries but has not help in developing countries. Various mycotoxins may occur simultaneously depending on the environment and substrate condition. Considering the co-incident production very likely, human are always exposure to mixture other than individual compound. Therefore, future risk assessment should be considering mixture toxicity data. This particularly true for ochratoxin A and ochratoxin B, Citrinin and occasionaly for patulin as they are all provided by a number of penicillium and aspergillus species. This review emphasis the different type of mycotoxins and their toxicological effect on health. The study on mycotoxin demonstrated their toxigenic, nephrotoxic, hepatotoxic, carcinogenic, immunosuppressive and mutagenic charasteristics.

Keywords: Mycotoxin, fungi, toxicological, health, aflatoxin, ochratoxin, fumonisin.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )