THE EFFECT OF “ZAROOR-E-QAWI” IN THE FORMATION OF THE HEALTHY GRANULATION TISSUE IN THE CASES OF THE CHRONIC WOUND: A SINGLE BLIND, NON RANDOMIZED PROSPECTIVE CLINICAL STUDY

*Dr. Md. Rizwanullah and Professor Saiyad Shah Alam

ABSTRACT

Back ground: Granulation tissue is the important component in the process of the wound healing. A wound can heal by the primary intention or by the secondary intention. In the chronic wound healing occurs through the secondary intention. The granulation tissue matrix fills up the gaps in the chronic wounds. Objectives: To evaluate the effect of the Unani formulation Zaroor-E-Qawi in the formation of the healthy granulation tissue in cases of the chronic wound. Material and methods: A single blind, non-randomised, prospective clinical study was carried out at National Institute of Unani Medicine, Bengaluru. The Patients in the age group of 18 to 70 years with chronic wound of Wagner’s grade-0, I and II were included in the study. After proper cleaning of the wound with normal saline, research drugs Zaroor-E-Qawi was sprinkled over the wound and dressing done. The assessment was done on every 15th day of the study. The protocol of the study was followed up to 45 days. Results: The means granulation tissue percentage on the baseline day was 35.16±30.11 which reached to 99.64±1.50% at the end of 45th day of the study. Statistically 96.7% of improvement was seen at end. Interpretation & Conclusion: The formulation Zaroor-E-Qawi is effective in the formation of the healthy granulation tissue in the chronic wounds, so this can be a novel modality in the treatment of the chronic wound.

Keywords: Chronic Wound; Healthy Granulation Tissue; Zaroor-E-Qawi.