EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

CHARACTERIZATION AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF COAGULASE-NEGATIVE STAPHYLOCOCCAL ISOLATES FROM A TERTIARY CARE CENTER

Komal Keswani*, Sourav Sen, Santosh Karade, Kyaw Zeyar Soe and R. M. Gupta

ABSTRACT

Background: Over past decade Coagulase-negative staphylococci (CoNS) have transformed from innocuous microbe to offensive pathogen causing hospital acquired infection. This study was carried out to ascertain antimicrobial susceptibility profile of CoNS isolated from clinical specimens of patients attending a tertiary care teaching hospital. Method: Consecutive clinical samples were processed for conventional culture from Jan 2019 to Dec 2019. Identification of CoNS up to species level and antimicrobial susceptibility testing was performed by VITEK 2 compact system. The gene implicated in resistance to cefoxitin (mec A) was identified by conventional PCR. Results: A total of 300 CoNS were isolated during study period of which S. epidermidis was predominant (43.3%). Methicillin resistance was seen in 86% of the isolates. A total of 64.7% of MR-CoNS(methicillin resistant coagulase negative staphylococci) showed presence of mec A gene. Conclusion: The study indicate emergence of multi drug resistance in CoNS isolates. Multiple genotypic resistance targets apart from mec A gene needs to be analysed to detect resistance in CoNS.

Keywords: Methicillin resistant coagulase negative staphylococci, mecA gene.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )