EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

ROLE OF SURVEILLANCE CULTURE IN MANAGEMENT OF NEUTROPENIC PATIENTS

*Dr. Sneha Sharad Bowalekar, MBBS, MD Microbiology

ABSTRACT

Context: Infections with Multi-drug resistant (MDR) organisms are often associated with increased morbidity and mortality in neutropenic children suffering from various cancers and undergoing chemotherapy. Aims: To assess the presence of MDR bacteria in stool specimen of children who were suffering from various cancers and were admitted for management to the hospital, in order to guide an earlier appropriate antimicrobial therapy. Methods and Material: The study involved pediatric patients of either sex diagnosed with different carcinomas treated at our hospital from June 2018 to January 2019. Stool cultures were sent within 72 hr of hospital admission and other cultures were sent when clinically indicated. MDR was defined as resistance of organism to >=3 classes of antibiotics. Results: A total of 55 stool surveillance samples from 50 pediatric patients showed presence of 67.14% MDR organisms. MDR E. coli was isolated at highest frequency. Equal prevalence of MDR organisms amongst both the sexes was observed (χ 2 = 0.96, P- value= 0.33). Blood cultures showed presence of both Gram positive and Gram-negative organisms. UTI was seen in 11 patients and 13.46% of MDR organisms were isolated from urine. Catheter tip culture isolated gram negative MDR organism. Very low concordance of 0% and 1.8% was found in blood culture and urine culture respectively with that of stool culture in isolation of same bacterial etiological agent. Conclusion: We do not recommend practical use of stool surveillance culture for management of febrile neutropenic patients. Studies are urgently needed to characterize in greater detail the exact colonisation rates in this population so that appropriate infection control, antimicrobial stewardship and treatment protocols can be implemented.

Keywords: Neutropenic, Surveillance, Stool, Children, management.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 November 2021 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR: NOVEMBER ISSUE PUBLISHED

    NOVEMBER Issue has been successfully launched on 1 November 2021.

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )