EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

FROM MARINE ORGANISMS AND PLANTS TO ANTICANCER AGENTS

*Mahadev G. Tate and Gayatri M. Saini

ABSTRACT

Marine organisms are potential source of drug discovery. Life has originated from the ocean that cover over 70% of the surface of earth and contain highly ecological, chemical, and biological diversity ranging from microorganism to vertebrates. This diversity has been the source of unique chemical compounds, which hold tremendous pharmaceutical potential. Generally drugs are obtained from the various species of bacteria, virus, algae, sponges, fungi etc. Marine flora and fauna, like algae, bacteria, sponges, fungi, seaweeds, corals, diatoms, ascidian etc. are important resources from oceans, accounting for quite 90% of the entire oceanic biomass. They are taxonomically different with huge productive and are pharmacologically active novel chemical signatures and bid an incredible opportunity for discovery of latest anti-cancer molecules. Ocean contain more than 3,00,000 invertebrates and algal species and rich in flora and fauna. Marine pharmacognosy is not a new area, even the early civilization of Japan, China, Greece and India have explored marine life as source of drug. During the past 35-45 years, Numerous novel compounds are isolated from marine organisms having biological activities like anti-inflammatory, anticoagulant, antiviral, antibacterial, anticancer and cardiovascular compounds. The aim of this review is to stipulate the paths of marine natural products discovery and development, with a special specialise in the compounds that successfully reached the market and particularly watching the approaches tackled by the pharmaceutical and cosmetic companies that succeeded in marketing those products. In this review, we summarized the contributions of marine natural products to treat CANCER via modulation of cancer-related factors involving oxidative stress, inflammation, and cell survival.

Keywords: Sponges, invertebrates, pharmaceutical, Marine, Modulation.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )