BACTERIOLOGY PROFILE OF NON-CATETHERIZED PATIENTS WITH BLADDER OUTLET OBSTRUCTION

Eziyi Amogu Kalu*, Oladele Solomon Olusola, Ojewuyi Olufemi Olayide, Oyeniyi Ganiyu Adebukola, Olopade Ifeoluwa Bolanle and Ore Hanna Egere

ABSTRACT

Background: Bladder outlet obstruction (BOO) is one of the commonest conditions seen by the Urologist. The prevalence is increasing, warranting effective management and prevention of complications. Objectives:
• To determine the bacterial organisms implicated in patients with bladder outlet obstruction.
• To determine the sensitivity pattern of empirical antibiotic used in this locality.
Materials and Method: A total of 102 patients were recruited for the study. The patient had urine microscopy, culture and sensitivity. Patients that were on antibiotics within the last 72 hours from time of sample collection and patients on catheter were excluded. Midstream urine samples were collected aseptically. Samples were processed within one hour after collection and cultured. Antibiotic susceptibility tests were carried out using modified Kirbby Bauer method.[1] Results: The predominant cause of the BOO was due to BPH (61.8%). A total of 22.5% of the patients had prior antibiotics more than three days before presentation to the hospital; 68.2% of the patients that used antibiotics used ciprofloxacin. The overall prevalence rate of bacterial organisms isolated in the urine of the subjects used for this study is 45.1%: Gram negative organisms were isolated in majority of the cases [78.2%]. The commonest organism cultured from the sample was Klebsiella sp. [43.5%]. The data was analyzed using SPSS version 22. Conclusion: The use of prophylactic antibiotics can be considered to be beneficial due to the increased susceptibility to urinary tract infection. Nitrofurantoin can be considered as an alternative to fluoroquninolones.

Keywords: Bladder outlet obstruction, Prostate specific antigen, Microbiology.