EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EVALUATION OF ANTIULCER ACTIVITY OF MORINGA OLEIFERA PODS EXTRACT

*Sukanya Pramod Paricharak and Dr. Shivakumar Hugar

ABSTRACT

The aim of current study is to evaluate antiulcer activity of the 70% hydroalcoholic extract of Moringa oleifera pods (HAEMOP) using different animal models of ulcer in rats. Pylorus ligation method was studied using Ranitidine (150mg/Kg) in rats as reference standard. The ulcer index, pH of gastric juice, volume of gastric juice was determined. Ethanol and aspirin induced ulcer was studied and the ulcer index was measured. In antiulcer studies, Moringa oleifera pods extract showed reduction in ulcer score each experimental model sucessessfully. In pylorus ligation ulcer model it also reduced gastric volume and increased pH of gastric juice. The results have shown that the Moringa oleifera pods extract contain some active ingredients with the potential of being antiulcer agents.

Keywords: Moringa oleifera, Pylorus Ligation Ulcer, Ethanol, Aspirin, Ulcer Index.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing