EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

A COMPARITIVE STUDY ON INCIDENCE AND FREQUENCY OF HYPOGLYCEMIC MANIFESTATIONS IN PATIENTS WITH UNCONTROLLED TYPE 2 DM WITH AND WITHOUT COMPLICATIONS AT A TERTIARY CARE HOSPITAL

Sreelekshmi S.*, Prabhad Sankar, Ginsha Fahim and Sreeja P. A.

ABSTRACT

Objective: To compare the incidence of hypoglycemic manifestations in uncontrolled type 2 DM with and without complication. To identify the frequency of hypoglycemia in uncontrolled type 2 DM patients with and without complication. To assess the hypoglycemic manifestations using Naranjo causality assessment scale. Subjects with uncontrolled type 2 DM (n=101) were included in the analysis. If the patient showed any clinical manifestations in that instant gross random blood sugar was taken and confirmed hypoglycemia. P value of FBS and GRBS to be calculated by Graph pad prism version 8.4.0 (671). Distribution of uncontrolled type 2 DM with complication is (34.65%) and uncontrolled type 2 DM without complication is (65.34%). Male (55.45) gender is more susceptible to uncontrolled type 2 DM than female gender (44.55). The age group between 50-59 of uncontrolled type 2 DM with complication (31%) and uncontrolled type 2 DM without complication (30.6%). FBS of ≤70mg/dL to be noted and p value is 0.034. GRBS of ≤70mg/dL to be noted and p value is 0.047. Nephropathy (37.14%) is major complication in uncontrolled type 2 DM with complication. Incidence of hypoglycemia in uncontrolled type 2 DM with complication (51.42%) and in uncontrolled type 2 DM without complication (34.84%).only one episode of hypoglycemia occurred in both uncontrolled type 2 DM with complication (50%) and uncontrolled type 2 DM without complication (60.86%).clinical manifestations of hypoglycemia varies with patient to patient. Hypoglycemia in uncontrolled type 2 DM with complication caused by insulin (50%) and in uncontrolled type 2 DM without complication caused by OHA (52.17%).On assessing the ADR (hypoglycemia)in uncontrolled type 2 DM with complication is definite(77.77%) and in uncontrolled type 2 DM without complication also definite (65.21%).

Keywords: Uncontrolled type 2 diabetes mellitus, complications, incidence, frequency , clinical manifestations of hypoglycemia.

[Full Text Article] [Download Certificate]