EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

A COMPARITIVE STUDY ON INCIDENCE AND FREQUENCY OF HYPOGLYCEMIC MANIFESTATIONS IN PATIENTS WITH UNCONTROLLED TYPE 2 DM WITH AND WITHOUT COMPLICATIONS AT A TERTIARY CARE HOSPITAL

Sreelekshmi S.*, Prabhad Sankar, Ginsha Fahim and Sreeja P. A.

ABSTRACT

Objective: To compare the incidence of hypoglycemic manifestations in uncontrolled type 2 DM with and without complication. To identify the frequency of hypoglycemia in uncontrolled type 2 DM patients with and without complication. To assess the hypoglycemic manifestations using Naranjo causality assessment scale. Subjects with uncontrolled type 2 DM (n=101) were included in the analysis. If the patient showed any clinical manifestations in that instant gross random blood sugar was taken and confirmed hypoglycemia. P value of FBS and GRBS to be calculated by Graph pad prism version 8.4.0 (671). Distribution of uncontrolled type 2 DM with complication is (34.65%) and uncontrolled type 2 DM without complication is (65.34%). Male (55.45) gender is more susceptible to uncontrolled type 2 DM than female gender (44.55). The age group between 50-59 of uncontrolled type 2 DM with complication (31%) and uncontrolled type 2 DM without complication (30.6%). FBS of ≤70mg/dL to be noted and p value is 0.034. GRBS of ≤70mg/dL to be noted and p value is 0.047. Nephropathy (37.14%) is major complication in uncontrolled type 2 DM with complication. Incidence of hypoglycemia in uncontrolled type 2 DM with complication (51.42%) and in uncontrolled type 2 DM without complication (34.84%).only one episode of hypoglycemia occurred in both uncontrolled type 2 DM with complication (50%) and uncontrolled type 2 DM without complication (60.86%).clinical manifestations of hypoglycemia varies with patient to patient. Hypoglycemia in uncontrolled type 2 DM with complication caused by insulin (50%) and in uncontrolled type 2 DM without complication caused by OHA (52.17%).On assessing the ADR (hypoglycemia)in uncontrolled type 2 DM with complication is definite(77.77%) and in uncontrolled type 2 DM without complication also definite (65.21%).

Keywords: Uncontrolled type 2 diabetes mellitus, complications, incidence, frequency , clinical manifestations of hypoglycemia.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing