EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

A PROSPECTIVE STUDY ON THE EVALUATION OF HEPARIN AND ITS ANALOGUES UTILIZATION IN A TERITIARY CARE HOSPITAL

Fayiza A.*, Sreeja P. A., Ann Suvi David and Fabiya Ibrahim

ABSTRACT

The objective of the study was to evaluate the utilization of heparin and its analogues in a teritiary care hospital. The prospective study was carried out in a total of 81 patients treated with heparin and its analogues. Details of inpatients who were treated with heparin and analogues were collected from patient files. Evaluation of demographic data revealed that 58% (n=47) were males while 42% (n=34) were females. A high percentage of patients aged between 59-68 years were found in the study population. Laboratory monitoring analysis shows that APTT test and INR test was done for 58%(n=47) of the total populations. The most prominent indication for which it was prescribed as Stroke 34.5%(n=28). The most commonly prescribed heparin analogue was Unfractionated Heparin(UFH). The commonly preferred route for administration was subcutaneous route 62.9%(n=51). In prescription analysis, it was found that maximum number of patients was receiving 5000 U (61.7%, n=50) of unfractionated heparin via subcutaneous route. During study period, the adverse drug reactions associated with heparin use were identified and monitored using Naranjo Causality Assessment Scale, 42 patients(51.8%) shown Adverse Drug reactions in the total population. The most common Adverse Drug Reactions were pain at injection site(19%) and Thrombophlebitis(19%).

Keywords: UFH, LMWH, APTT, INR, subcutaneous route.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing