EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

MORPHINE SULFATE EXTENDED RELEASE TABLETS A SEMINAR REPORT

*Hafsa Fatima, Syed Aietesam, M. PHARM, and Prof. Dr. Syedabdulazeez M. Pharm Ph.D

ABSTRACT

Tablets are intended for oral administration. Some tablets are swallowed whole or after being chewed, some are dissolved or dispersion in water before administration and some are retained in mouth where the active ingredient is liberated. Preparation intended for administration by other routes, for example, in the form of implants and passerines may also be presented in the form of tablets but because they may required special formulations, methods of manufacture or from of presentation appropriate to the particular use they may not comply with all the requirement of this monograph. Morphine is a pain medication of the opiate family which is found naturally in a number of plants and animals. It acts directly on the central nervous system (CNS) to decrease the feeling of pain.It can be taken for both acute pain and chronic pain It is frequently used for pain from myocardial infraction and during labor. Morphine was first isolated between 1803 and 1805 by friedrichserturner. This is generally believed to be the first isolation of an active ingredientsfrom a plant. merck began marketing it commercially in 1827. Morphine was more widely used after the invention of the hypodermic syringe in 1853–1855. Serturner originally named the substance morphiumafter the Greek god of dreams, morpheus, as it has a tendency to cause sleep. The primary source of morphine is isolation from poppy strawof the opium poppy. In 2013, approximately 523 tons of morphine were produced. Approximately 45 tons were used directly for pain, a four-fold increase over the last twenty years. Most use for this purpose was in the developed world. About 70 percent of morphine is used to make other opioids such as hydromorphone, oxomorphone and heroine It is a Schedule II drug in the united states, Class A in the united kingdom and Schedule I in canada. It is on the medicinal health of organisation list of essential medicines, the most effective and safe medicines needed in a health system. Morphine is sold under many trade name. In 2016, it was the 158th most prescribed medication in the United States, with more than 3 million prescriptions.

Keywords: Friedrich serturner, merck, hypodermic syringe, Morpheus, hydromorphone, oxymorphone.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia