SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NOVEL BISARYLAMINO THIAZOLOYL BENZOTHIAZOLES
B. Jini Kumari and T. F. Abbs Fen Reji*
A series of 2-[2,4-bis(aryl/alkylamino)thiazol-5-oyl]benzothiazole derivatives were synthesized from 1-aryl-3-(N,Nâ€™-diarylamidino)thioureas and 2-(2-bromoacetyl)benzothiazole with triethylamine. Their structures were established on the basis of IR,1H NMR, 13C NMR and mass spectral analyses. All the synthesized compounds were screened for their antibacterial and antifungal potential. All the compounds showed significant activity against the microorganisms tested.
Keywords: Benzothiazoles, Antibacterial activity; Antifungal activity; Triethylamine.
[Full Text Article]