( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Ahmed M. Elsadig*, Mohammed A. Hammad, Salahaldeen H. Dahawi, Dr Mohammed Ahmed Abd Allah, Hisham N. Altayb


Introduction: Carbapenemase producing bacteria represent a challenging problem for health care providers, particularly in acute-care and long-term-care facilities and more in community- acquired infections. In contrast to other Enterobacteriaceae (e.g., Escherichia coli, Klebsiella pneumoniae and Enterobacter, which are major nosocomial pathogens affecting debilitated and immunocompromised patients, carbapenem resistance is still very rare in non-typhoidal salmonella serovars. Methods: 101 enterobacteriaceae clinical isolate were collected at different hospitals and 8 food handlers’ clinical samples were received from central laboratory management in Khartoum State. Identification of the isolates was done by using conventional biochemical methods, and antimicrobial sensitivity testing was done according to CLSI guidelines. Isolates were then tested for the presence of carbapenemase encoding genes using multiplex PCR with specific primers for the detection of OXA-48 and KPC genes. Result: Out of the 109 isolates Escherichia coli and Klebsiella sp. demonstrated the majority with 43 % and 35.7 % respectively. Carbapenem resistance was demonstrated in 31 (28%) of the isolates. The presences of OXA-48 and KPC genes was confirmed in 40/109 (29%) of the isolates. Conclusion: The study concluded the evidence of the presence of the KPC and OXA-48 genes, further studies and a regular monitoring system for early detection of Carbapenemase-producing organisms are recommended with continuous surveillance of resistance to these ―last resort‖ antibiotics.

Keywords: Carbapenem resistant enterobacteriaceae, carbapenemase producing enterobacteriaceae, KPC, OXA, multiplex.

[Full Text Article]



  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 December 2021 Issue has been Published, Kindly check it on


    DECEMBER Issue has been successfully launched on 1 December 2021.

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )