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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

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European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Eyimi Abessolo François G.*, Ndoe Guiaro Marcellin, Atenguena Etienne, Ndom Paul and Bengondo Charles


Nowadays, surgery, radiotherapy, and chemotherapy are the most used cancer therapies. But the chemotherapy, because of its non-specificity towards neoplastic cells causes many complications among which the oral complications. About 40% of chemotherapy patients develop an oral complication and, this prevalence can go up to 76% in malignant hemopathies. In this study, our objectives were to determine the prevalence, frequency and average extension time for the occurrence of these complications at the Yaounde general hospital. In the other hand, the association of these complications with a few risk factors was evaluated. To achieve these objectives, we conducted a descriptive study over 6 months with prospective data collection in the oncology department of the General Hospital of Yaounde. Our sample was determined consecutively and randomly. The selected patients (1 patient = 1 file), after receiving their chemotherapy cure, were consulted on the 10th day to identify the sprung complications. When a statistical test was required, a value of p˂0.05 was considered to be statistically significant. 95 participants (36 men and 59 women) were included in our study. The prevalence of oral complications was 40%. and, four types of toxicity were observed in this population namely: the mucositis (44.74%), the xerostomia (26.32%), the dysgeusia (23.68%) and the oral candidiasis (5.26% ). These complications occurred after an average extension time of 08 days and seemed to be frequent in the female sex and in the age group of 30 to 40 years. The risk factors associated with these complications were: the young age (p = 0.025), the unpleasant oral health (p = 0.049; OR = 3.27; CI = [1.09-9.80] and HIV infection (p = 0.01; OR = 4.78; CI = [1.39-16.41]. Thus, chemo-induced oral complications are a reality in Cameroon with a prevalence of 40% reported at the end of this study.

Keywords: .

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )