ALOEVERA MUCILAGE USE AS A BINDING AGENT FOR POORLY COMPRESSED DRUG

Sonal Gupta*, Jagrati Chaurasia, Fouziya Hussaini, Khushi Malviya and Dr. Kuldeep Ganju

ABSTRACT

Now a days, an oversized range of pharmaceutical excipients are obtained from natural sources. Mucilages and their derivatives square measure a group of polymers extensively used in pharmaceutical dosagee forms. it acts as pharmaceutical adjuvants. A study was carried out to investigate the possibility of extracting aloe mucilage from the leaves of Aloe barbadensis and using it as a binding agent in metronidazole tablets. The binding properties of the gum extracted were investigated in lactose based metronidazole tablet formulations at completely different binder concentrations of 1%w/w, 2%w/w, 4%w/w. The present review discusses the expansive sources of mucilage, its versatile excipient property as tablet binders, disintegrating, emulsifying, suspending, gelling, stabilizing, thickening and sustained release agent obtained from aloe plants which adds an different pharmaceutical property to its uses.

Keywords: Aloe barbadensis, binders, tablets, Mucilage, Excipients.