EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

OXIDATIVE STRESS REACTIVE OXYGEN SPECIES AND ANTIOXIDANT DEFENSE SYSTEM IN PERIODONTITIS - A REVIEW

Dr. Anju Gautam* MDS, Dr. Neelam Mittal MDS and Dr. S. P. Mishra

ABSTRACT

Periodontitis is an inflammatory disease that results in the destruction of supporting periodontal tissues of the teeth, which is primarily initiated by bacterial infection and subsequently modified by anomalous (abnormal, aberrant) host response. As the oxidants and antioxidants are in dynamic equilibrium, any disturbance in one would lead to oxidative Stress. Whenever periodontitis occurs, reactive oxygen species are produced mostly by hyperactive neutrophils that could not be neutralized by antioxidant defense system, cause tissues damage. This tissues damage is mainly characterized by increased lipid peroxidation, DNA damage and protein damage leading to formation of oxidative stress markers. This article focuses on the reactive oxygen species, oxidative stress markers and antioxidant defense system in periodontitis.

Keywords: Reactive oxygen species, Antioxidants, Oxidative Stress.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing