EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

RED BLOOD CELL DISTRIBUTION WIDTH (RDW) AS A PREDICTIVE BIOMARKER FOR PATIENTS WITH MYOCARDIAL INFARCTION IN SUDAN

Eman Elimam Diab, Elharm Ibrahim Abdallah and Mohamed Mobarak Elbasheir*

ABSTRACT

Background: Red blood cell distribution width (RDW) is a simple and inexpensive parameter, which measures the range of variation of erythrocyte volume (anisocytosis) and routinely used in complete blood count for differential diagnosis of anaemias. Emerging reports suggest a usefulness of RDW in multiple clinical applications, including coronary artery disease (CAD). Therefore, early detection and intervention in time of these vascular diseases is critical for delaying their progression. So, the current study is aimed to assess the predictive value of RDW in the diagnosis of Myocardial infarction. Materials and Methods: One hundred and twenty individuals (mean age 58.5 years, 70 males, 50 females) in Khartoum state were enrolled into this study. They divided into (60 patients with known myocardial infarction admitted at AL-Shaab Teaching Hospital as a case group and 60 healthy individual as control group. All blood samples were collected in EDTA container and RDW was measured by (Sysmex KX21N) hematology analyzer, then data were analyzed by SPSS. Results: There was a high significant increase in RDW among cases when compared to control with P value (0.00). In addition, A significant positive correlation between RDW and age among patients with myocardial infarction was observed (R value 0.465, P value 0.000) while negative correlation was detected in control group (R value − .067, P value 0.617). Conclusions: RDW is a simple biomarker that could be used for early prediction of myocardial infarction and furthermore for prognosis of patients with heart disease.

Keywords: Red cell distribution width, Myocardial Infarction, Predictive Biomarker.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing