EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

COMPARATIVE EVALUATION OF FLAX SEED AND CHLORHEXIDINE MOUTHWASH IN THE TREATMENT OF GINGIVITIS – A CLINICO-IMMUNOLOGICAL STUDY

*Dr. Georgina George Ettiyil, Dr. Harsha Mysore Babu, Dr. Vivekananda M. R., Dr. Shivaprasad D., Dr. S. Ravindra

ABSTRACT

Background and Objectives: One of the noteworthy developments in this age of dentistry is that the dental practice is based on preventive measures and the surfacing of a philosophy. Chemical agents have been advocated as adjuncts to mechanical methods to augment the plaque control. Flax seed is known for its anti-inflammatory action. Studies evaluating its effects on gingivitis are scarce. Hence, the present study was aimed to compare and evaluate the efficacy of Flax seed as an anti-inflammatory agent with chlorhexidine gluconate in the treatment of plaque induced gingivitis. Materials and Methods: In this randomized controlled clinical trial, 30 subjects were randomly assigned to two groups with 15 subjects in each group, Group A received Scaling+ Flax seed mouthwash and Group B received Scaling + Chlorhexidine mouthwash. Clinical parameters like Plaque index (PI), Gingival index (GI), Sulcular Bleeding Index (PBI) and immunological parameters i.e., Interleukin-6 (IL-6) levels were assessed at baseline and at one month. Statistical analysis was carried out using SPSS software 2.0. Results: The results of the current study showed that the mean scores of PI, GI, SBI and the levels of IL-6 at baseline and at one month had consistently decreased to lower values in both Group A (7.586 ± 4.04) and Group B (11.716 ± 8.19) which was statistically significant on intragroup analysis. The results from baseline to one month were comparable on intergroup analysis with no statistically significant difference. Conclusion: Flax seed mouthwash was found to be equally effective as chlorhexidine gluconate in treating chronic generalized gingivitis.

Keywords: Flax seed, Mouthwash, Gingivitis, Chlorhexidine Gluconate, Interleukin-6.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )