PREVALENCE OF SERUM MAGNESIUM LEVELS IN PATIENTS OF ACUTE MYOCARDIAL INFARCTION AND IT'S ASSOCIATION WITH VENTRICULAR ARRHYTHMIA AS A COMPLICATION

Dr. Sumit Kant Jha, *Dr. Shivang Sharma and Dr. Saurabh Singhal

ABSTRACT

Aim and Objective: TO STUDY THE PREVALANCE OF SERUM MAGNESIUM LEVEL IN PATIENTS OF ACUTE MYOCARDIAL INFARCTION AND ITS ASSOCIATION WITH VENTRICULAR ARRHYTHMIA AS A COMPLICATION. Material Method: The present prospective observational study was conducted in the department of Medicine at Chattrapati Shivaji Subharti Hospital from 2017 to 2019. -The study group comprised of 50 patients with acute myocardial infarction. Patients were enrolled in the study On the basis of inclusion and exclusion criteria and after obtaining written informed consent from parents and approval from Institutional Ethical Committee. Results: Serum magnesium level (mg/dL) i.e. <1.6, 1.7-2.4 and >2.4 was found in 40%, 60% and 0% of the subjects respectively on day 1. Sixteen percent (8) of the subjects with arrhythmia were having serum magnesium level (mg/dL) <1.6 while only 4% of the subjects with arrhythmia reported 1.7-2.4 serum magnesium level (mg/dL). It can be said that patients with acute myocardial infarction with low magnesium level are more prone to develop ventricular arrhythmias compared to those who are having normal magnesium levels. Magnesium replacement therapy in patients with acute myocardial infarction who is having low serum magnesium level may reduce the incidence of arrhythmias. Conclusion: Serum magnesium levels on admission were significantly low in patients of arrhythmia as compared with or without arrhythmia. Hypomagnesemia is often associated with arrhythmia. Magnesium therapy reduces the incidence of arrhythmias and mortality even in the absence of demonstrable magnesium deficiency. The present study is a good enough reason to include I.V. magnesium sulfate as an add-on prophylactic treatment in the acute coronary syndrome’s management protocol.

Keywords: Hypomagnesemia, magnesium sulphate.