EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EVALUATION OF ANTI-CANCER ACTIVITY AND PHYTOCONSTITUENTS OF BIOPHYTUMSENSITIVUM LINN: AN INVITRO STUDY

Tharani M.*, Tamilselvan T., Ponnudurai K., Malaisamy N., Vignesh Mirthick R., Wafa Ahmed Saadeldin Badr and Sabari Murthy V.

ABSTRACT

Objective: In the current research phytochemical and invitro, anticancer activity was evaluated using petroleum ether extract and methanol extract of Biophytumsensitivum Linn. Materials and Methods: The whole plant was dried for fifteen days and grounded using mechanical blender. The extraction was carried out using the Soxhlet apparatus with 10 volumes of 75% Methanol and another extraction with Petroleum Ether (10 volumes of 75% solution). The extract was evaporated and dried. Preliminary phytochemical screening and FTIR techniques were performed to identify the basic components. Using DLA and EAC cell lines the anti-cancer activity was carried out. Results: The whole plant showed the presence of phenols and flavonoids at a higher rate than steroids, glycosides, and Ketones. Its presence was confirmed using FTIR reports. The cytotoxicity studies were highly significant in Methanol extract of Biophytumsensitivum Linn than Petroleum Ether extract. Conclusion: The effective anti-cancer activity was reported in the whole plant Methanolic extract of Biophytumsensitivum Linn as compared with petroleum ether extract. Further specific studies are required to find out the specific individual components.

Keywords: Biophytumsensitivum Linn, Phytochemical screening, DLA, EAC cell lines.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database