EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

OVERVIEW OF PAPERS PUBLISHED ON THE FORMULATIONS OF OLANZAPINE API

Dr. Shubhangi C. Daswadkar* and Abhijit Vasant Atole

ABSTRACT

Olanzapine is an Antipsychotic drug used for the treatment of Schizophrenia disease. Nowadays Schizophrenia disease is increases day to day because of having very modern life. Olanzapine is a class II atypical Antipsychotic drug which having Low solubility and High permeability. Due to that, there bioavailability also decreases and so that the amount of drug which is required for the treatment of Schizophrenia cannot get. So for that reason there are some researchers worked on that disadvantage and tried to get a good bioavailability and hepatic first pass metabolism. For that purpose they discovered the new dosage forms like Olanzapine Injection, Olanzapine Tablets in that category there also different types such as Sustained release tablets, Orodispersible tablets, Matrix pellets, Sustained release matrix tablets, Mouth dissolving tablets, Micro emulsions, Polymeric Nanoparticles, Solid Lipid Nanoparticles, Quick dispersible tablets, Olanzapine Microspheres, Solid Dispersion. With using of that type of dosage forms they get good bioavailability and good hepatic first pass metabolism also get direct treatment to brain by brain targeting nanoparticles. The main objective of that review article is to provide information regarding the, which dosage forms are already prepared on Olanzapine API which are helpful to the students for the literature review in future.

Keywords: Antipsychotic, Olanzapine, Schizophrenia, bioavailability, Nanoparticles.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )