IN-VIVO PHARMACOLOGICAL ACTIVITIES OF METHANOL EXTRACT OF RHODODENDRON ARBORETUM (LEAVES) ON EXPERIMENTAL MICE

Mohammad Moniruzzaman*, Mohammed Tareq Aziz, Md. Ariful Mondol Arif, S. M. Farzana

ABSTRACT

The point of this examination was to explore the analgesic, anti-inflammatory and hypoglycemic exercises of methanol concentrate of Rhododendron arboretum leaves alongside the nearness of significant phytochemicals. The rough leaf concentrate of Rhododendron arboretum was examined for analgesic, anti-inflammatory and hypoglycemic exercises utilizing different exploratory models. Against diabetic movement was dictated by Oral Glucose Tolerance Test (OGTT). To decide the analgesic movement, acidic corrosive actuated squirming model was utilized on mice. For anti-inflammatory movement test Inflammation (paw edema) was actuated by infusing 0.1ml of 1% Carrageenan. The concentrate caused a significant portion subordinate decrease of glucose, aggravation and torments instigated by various operators utilized. The phytochemical screening demonstrated the nearness of glycoside, alkaloid, flavonoid, saponin, tannin and steroid kind of mixes. Leaf separate has calming and pain relieving impacts which might be intervened through the phytochemical constituents of the plant.

Keywords: Rhododendron arboretum, Hypoglycemic activity, Analgesic activity, Anti-inflammatory activity, Carrageenan.