A HYPOTHESIS THAT CORRELATE MOLECULAR WEIGHTS AND NUMERICAL TECHNIQUES AS AN OPTIMIZATION TOOL TO DESIGN ESTERS WITH POTENTIAL ANTICANCER ACTIVITY
Luay Rashan, Heinz-Herbert Fiebig, Gerhardt Kelter, Thabit Sultan Mohammed, Ahmmed S. Ibrahim, Talal Al-Allaf and Rafie Hamidpour*
The present work relates to a hypothesis that correlates between the molecular weights and the application of numerical techniques such as Newton-Raphson for the first time as an optimization tool to design water soluble esters with potential anticancer activity in vitro and in vivo. The results obtained from this application suggested a consistent and clear correlation between the experimental and numerical analysis results. However, further studies are required to confirm this correlation.
Keywords: Hypothesis, Correlation, Molecular weights, Numerical Techniques, Esters, Anticancer Activity.
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