NEPHROPROTECTIVE ASSAY MODELS: A REVIEW
A. K. Anjana, P. L. Rajagopal*, P. N. Sajith Kumar, I. Arthi, Meera B. Nair and S. Aneeshia
Nephrotoxicity is one of the major cause that affects the mankind resulting from the use of medications or from the use of diagnostic agents. It is mainly due to the accumulation of toxic chemicals and delayed excretion of the same from the body by the kidneys. It may lead to several other diseases and even can be fatal. Nephrotoxicity can be assessed by using different study models so that the safe dose of drugs can be determined to be used safely in the humans. Animals are used for the assessment and from the studies the effective and toxic doses of the chemicals can be found out.
Keywords: Nephrotoxicity, animals, drug.
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