EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

3D PRINTING TECHNOLOGY FOR TABLETS: OPPORTUNITIES & CHALLENGES

Rameesha N. K.*, Sirajudheen M. K., Shiji Kumar P. S. and Sherin A.

ABSTRACT

The 3D printing has a role in medical devices industry & pharmaceutical industry due to its application on various channels of health care industry. It has become one of the most revolutionary & powerful tool serving as a technology of precise manufacturing of individually developed dosage forms, tissue engineering & disease modeling. This technology exist for a long time it is of public interest highly now due to the approval of 3D printed tablet, other medical devices & also with the arrival of USFDA‘s guidance on technical considerations specific to devices using additive manufacturing with possess 3D printing has triggered many thoughts about this technology which needs to be considered for successful delivery of intended product. This review summarizes the newest achievement & challengers of additive manufacturing in the field of pharmaceutical & biomedical research that have been published since 2015. Currently developed techniques of 3D printing are briefly described while extensive analysis of extrusion – based methods as the most intensively investigated is provided. And also this paper presents regulatory agencies expectations, limitations, problems in establishing such setups in production of drug products, advantages, disadvantages, applications, methods and associated risks involved in manufacturing. The issue of printlets attributes,I.e. shape & size is described with regard to personalized dosage forms and medical devices manufacturing. The undeniable benefit of 3D printing are highlighted, however a critical view resulting from the limitation & challenges of the additive manufacturing is also included. It provides the extensive review of the current status of research and development on this platform. As well as the regulatory issue is pointed.

Keywords: 3d printing, FDM method, Spritam.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia