EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

A STUDY OF CORELATION OF CLINICAL PROFILE WITH BIOCHEMICAL & RADIOLOGICAL INVESTIGATIONS IN ACUTE PANCREATITIS

Dr. Santosh Dalavi and Dr. Swapnil Chopade*

ABSTRACT

Introduction: Acute pancreatitis is a common condition involving the pancreas. Gall stone disease and alcohol account for greater than 80% of all patients with acute pancreatitis, with biliary disease accounting for 45% and alcohol found in 35% of patients1 Acute pancreatitis includes a wide spectrum of disease, from one with mild self- limiting symptoms, to fulminant processes with multiorgan failure and high mortality. Given the wide spectrum of disease seen, the care of patients with pancreatitis must be highly individualized. Primary Objective: To study of correlation of clinical profile with biochemical & radiological investigations in acute pancreatitis. Secondary Objective: To study the outcome of treatment and complications of acute pancreatitis. Methods: After admission to the hospital, a detailed clinical history and examination of the patient was done. Routine investigations like Complete hemogram, Blood urea, Serum amylase; serum lipase were performed. USG Abdomen and contrast CT ABDOMEN. The patients were classified as having mild acute pancreatitis or severe acute pancreatitis. The treatment plan was focussed on adequate initial resuscitation and supportive care, early detection of complications and definitive treatment of the associated biliary disease. Observations & Results: Serum Lipase was the diagnostic test with a sensitivity of 0%. Serum amylase is a strong indicator of development of pseudocysts as 70% of patients with levels more than twice the upperlimit developed pseudocysts. Ultrasonography visualized pancreas on about 92% patients with findings of acute bulky oedematous & bulky hypoechoic pancreatitis whereas CT visualized pancreas in 100% patients. CT is a confirmative investigation in diagnosis and staging of Acute pancreatitis. CT Severity Index is prognostic score in assessing severity & outcome of disease. Conclusion: Acute pancreatitis is a clinical diagnosis supplemented by serum amylase, serum lipase, Ultrasonography & CECT. Ultrasonography visualized pancreas on about 92% patients and its limitations were overcome by CECT.

Keywords: .


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )